In Vitro In Vivo Translation Industrial Placement 2022

With over 300 years of innovation, we’re a science-led global healthcare company that discovers, develops and manufactures innovative medicines and vaccines. Our industrial placements are real roles with real responsibility, where you can gain experience in a purpose-led, performance-driven healthcare business. Join us and help millions of people do more, feel better, live longer.

Want to solve some of the world’s biggest health challenges? 

GSK are a science-led global healthcare company that researches and develops innovative Pharmaceuticals and Vaccines products. Our challenging and inspiring mission is to enable people to do more, feel better and live longer by developing innovative products and improving access to healthcare for patients around the world.

Whatever the role, you will experience working in a fast-paced research environment with access to cutting edge technology, whilst interacting with industry-leading scientists across multiple disciplines and sharing different experiences. During the internship, you will be supported and given training (laboratory and office practices, where applicable) until confident to work independently - with a focus on GSK health and safety requirements.  You will be enrolled in GSK internal courses to develop your knowledge of company policy and for your personal development including opportunities to attend seminars led by GSK scientists and networking opportunities.

Mass Spectrometry Imaging Analyst Role

The main focus of the MALDI Bioimaging group is to employ state-of-the-art technologies in mass spectrometry imaging to investigate the spatial distribution of drugs and drug related molecules in tissue.

• You will work as part of a team to provide critical data to progress the development of new medicines across a range of programmes from different therapeutic areas.  
• You will have an opportunity to undertake a specific project combining MALDI mass spectrometry imaging and transcriptomics to study the detailed characterisation of endogenous compounds under different stimuli or treatments. 
• You will contribute to the development of this exciting technology and will prepare ex-vivo tissue samples and utilise state-of-the art mass spectrometers for the analysis of these samples. 
•  The successful applicant will receive full training in the techniques involved and will investigate the spatial distribution of drug related molecules in tissues. 

Global Investigative Safety (Non-clinical safety) Role

• The placement will be positioned within the Global Investigative Safety group within Non-Clinical Safety.  The group are involved in the design and execute bespoke transcriptional and cellular assays to investigate and validate mechanistic hypotheses regarding safety across all phases in the drug development process. 
• Team members have expertise in mitochondrial, lysosomal, gastrointestinal and liver toxicity.  
• The project will allow the further development of skills in in vitro cell culture, working with cell lines or primary cells.   
• The project will include using a wide range of techniques typically used within the laboratories, of which you will receive training, including aseptic technique and may include specifically, measuring cytotoxicity using a range of multiparametric plate-reader assays, transcriptomics, bioenergetic assays and high content imaging analysis to explore and identify mechanisms of toxicity.  This will aid current and future projects with decision making regarding the development of compounds. 

Genetic Toxicology & Photosafety Role

There is overwhelming evidence that inherited mutational changes in humans are responsible for genetically determined diseases and congenital (heritable) malformations. Also, the accumulation of somatic cell mutations is known to be implicated in cancer, and to some extent in other multi-factorial diseases. As novel drugs may represent a potential source of damage to DNA, appropriate testing is required to minimise the risk of genotoxicity for both ethical and legislative reasons. The discipline of genetic toxicology as applied to drug development exists to achieve this aim.

Students undertaking a placement in genetic toxicology will perform investigative studies associated with the work of the dept, in the form of a research project. This will consist of literature reviews and establishment of expertise in one or more of the following technologies: flow cytometry, bacterial and mammalian cell/tissue culture, microscopy and image analysis. Following appropriate training, students will be expected to conduct independent research, collate/analyse experimental data, write summaries/reports and a dissertation at the end of year. They will also be expected to present the results of their work at the annual students review and external meetings, if appropriate. 

In addition, working alongside highly experienced genetic toxicologists, students will develop knowledge of the drug development process, the role of safety assessment and genetic toxicology; be involved in general laboratory management duties throughout the year to gain valuable experience in the daily workings of an industrial genetic toxicology lab to directly support the screening of potential new medicines; develop scientific, IT and other core skills. 

Additional Details

The Assessment Centres for successful applicants are expected to take place in February and March 2022 and the placement wil last for one year (approximately).

Degree requirements

You will have completed a minimum of 2 years of your undergraduate degree; but will not have graduated at the start of your placement. You may be expected to provide evidence from your university to show you will be an undergraduate student for the duration of the placement year and they are supportive of your placement. 

You must be undertaking a Life Sciences degree in a Chemistry, Biochemistry, Biology related field. 

Benefits

• A salary of £21,000 plus a bonus  
• Access to GSK resources such as employee assistance programmes, private healthcare, and training and development.  

Application Deadline

We recommend you apply as soon as possible, because we accept ongoing applications and will close this vacancy once we have enough applications.

We are recruiting for multiple roles within this advert. When you apply you will be able to select 3 preferences. We will accommodate your preferences where possible. 

Get to grips with our Recruitment Process

If you have what we’re looking for apply today!

This opportunity has the following recruitment stages you must successfully pass to be offered a placement year with GSK for 2022:

• Eligibility Form
• World of GSK Online Assessment
• Application Form
• Virtual Assessment Centre  

For Industrial Placements that involve lab-based work, working with human biological samples the student must be Hepatitis B vaccinated to work within these labs. Hepatitis B vaccination is entirely voluntary.  If you decide not to be vaccinated, your decision will be fully respected.  You will be given appropriate project work, but would not be able to work with human biological samples.  It’s critical we follow the appropriate health and safety guidelines to all employees safe.

You’ll find hints, tips and guidance on our recruitment process on our website. We have changed the way we recruit in light of the COVID-19 pandemic, you can learn more about how our practices have adapted here. 

We’re 100% open to all talent – whatever your gender, marital status, religion, age, colour, race, sexual orientation, nationality or disability. We want to recruit the right people for GSK from the widest possible backgrounds, so we can better serve the diversity of our patients and consumers. And also because it’s the right thing to do. You can learn more about Inclusion and diversity at GSK here.

Need help with your application?

Please email us at  UK.InternRecruitment@gsk.com and let us know how we can help you. Or email us your number and we’ll call you back. We’ll make all reasonable modifications to support you throughout the recruitment process and we’ll treat all information you give us in confidence. Please get in touch to help us process your application as soon as possible. 

As a company driven by our values of Patient focus, Transparency, Respect and Integrity, we know inclusion and diversity are essential for us to be able to succeed. We want all our colleagues to thrive at GSK bringing their unique experiences, ensuring they feel good and to keep growing their careers. As a candidate for a role, we want you to feel the same way.

As an Equal Opportunity Employer, we are open to all talent. In the US, we also adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race/ethnicity, colour, national origin, religion, gender, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class*(*US only).

We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are.

Please don’t hesitate to contact us if you’d like to discuss any adjustments to our process which might help you demonstrate your strengths and capabilities.  You can either call us on 0808 234 4391, or send an email ukdiversity.recruitment@gsk.com

As you apply, we will ask you to share some personal information which is entirely voluntary. We want to have an opportunity to consider a diverse pool of qualified candidates and this information will assist us in meeting that objective and in understanding how well we are doing against our inclusion and diversity ambitions. We would really appreciate it if you could take a few moments to complete it.  Rest assured, Hiring Managers do not have access to this information and we will treat your information confidentially.

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